John Hall’s manuscript is the one record we have of his authentic voice. This section describes the manuscript and summarises its history. But what do we mean by ‘a casebook’? The term as used by historians covers works of mixed and fluid genres. Hall’s work differs from the majority of casebooks because it represents his draft towards a book he never finished. It shows that a casebook can have an internal structure related to the chronologies of its composition as well as to the cases from which it draws. Hall is not unique in his substantial borrowing from Latin texts, though he does represent an extreme and very rare example. His manuscript is especially valuable because it represents a work in progress, an early modern physician’s mind in the process of thinking about his patients, his conversations with them and his treatments. This first complete English translation presents a highly readable work, full of human interest, insight and compassion. This section of the introduction also outlines the themes of Hall’s casebook and shows how Hall interacted with his patients. This section represents original scholarship in its new understanding of Hall’s manuscript, his Latin, and what it represents in an historical context.