This article explores in what ways and to what extent it is possible to talk about ‘higher learning’ and ‘higher education’ in Manchester before 1824, the date formally chosen by the University of Manchester to mark its foundation. It considers diverse sites and institutions, revealing a complex, interconnected web of knowledge spaces – dissenting academies, teaching hospitals, learned societies, independent libraries and individual initiatives – which complicate existing narratives of the development of higher education in the city that usually focus on the origins of the university. In the early nineteenth century, with Manchester rapidly becoming the ‘world’s first industrial city’, we see emerging at the same time a vibrant urban educational landscape, with no parallel in the British Isles at that time. 1 In contrast to England’s ancient universities which remained, for the most part, closed and private entities until the mid-nineteenth century, Manchester’s educational culture was self-consciously diffused, civic and participatory, strongly influenced by the city’s prominent dissenting communities. Excluded from Oxford and Cambridge, Manchester’s Unitarians, in particular, sought to shape the city’s educational culture according to the Enlightenment ideal of polite learning as a public endeavour. While civic participatory models have been foregrounded by historians of knowledge and ideas in recent years, this article considers, for the first time, how such models influenced the history of educational cultures in Manchester.