David Lloyd Roberts MRCS LSA MD FRCP FRS.Edin (1834–1920) was a successful Manchester doctor who made significant contributions to the advancement of gynaecology and obstetrics. His career was closely linked to the Manchester St Mary’s Hospital for Women and Children, 1858–1920. He lectured on midwifery at Owens College and the University of Manchester and was gynaecological surgeon to Manchester Royal Infirmary. He had many interests outside medicine, including a large collection of rare books, paintings and antiques. He produced an edition of Thomas Browne’s Religio Medici (1898) and a paper, The Scientific Knowledge of Dante (1914). He donated his books to the John Rylands Library and the London Royal College of Physician, his paintings to the Manchester Art Gallery, and he left a large endowment to Bangor College, Wales. This article reviews his medical work alongside his legacy to literature, the arts and education.